TABLET PRESS (R&D – Large scale production)

"XP1" R&D single punch tablet press machine

XP1 is a single-punch tablet press machine designed for R&D, feasibility studies, screening, and product characterization investigation.

Since characteristic surveys can be easily performed with simple settings and a small amount of powders, product development and powder analysis are possible with a lot of flexibility.
By the open design, the machine is very user-friendly to use, which makes it easy to change the format and clean. Since the filling depth and insertion depth can be adjusted with high precision, the tableting parameters can be easily changed even during running the machine.
The newly developed tool adapter supports both TSM and EU standard tooling, and due to that, XP1 can produce tablets of a wide range of sizes from minitabs to large tablets with a diameter of 25 mm.

XP1 can be configured in three types: a normal type, a benchtop type and a portable type with casters.
The latest data acquisition and analysis system can be also installed, which is making the XP1 the ultimate tableting machine in the field of R&D.

"XL100" Clinical and small-scale production rotary tablet press machine

XL100 is a rotary tablet press machine for R&D, clinical production, scale-up and small scale production, which means very versatile in operation.

The turret is replaceable and the tablets of all sizes can be manufactured. A mix-turret can be installed as an option, and both B and D tools can be used with the same turret.
Although it has a very compact mechanical design such as no compression corner column and the electrical cabinet integrated on the back of the machine, it has an excellent accessibility to the compression area, and it is also excellent in format change and cleaning.
XL100 also has the functions required for production, such as main compression force trend display, automatic compression force control, and single sorting (single reject function for bad tablet by compressed air), and thus can be used for clinical and small-scale production.

XL100 Pro has a internal PC, thus is able to add additional features such as a 15-inch touch screen, tabletting data acquisition and storage functions, automatic weight control, and recipe storage.

"X3" Middle-scale production single side rotary tablet press machine

X3 is a single side rotary tablet press machine for single-layer / Bi-layer tablet. This machine is ideal for scale-up, clinical production, medium-scale production and continuous production.

KORSCH's know-how not only the features such as mix-turret, low noise and vibration level, machine integrated electrical cabinet, and Through-the-wall installation, furthermore, the user-friendly design concept such as cleanability, maintainability and accessibility, as before, but also it realizes further foot-print saving and superior production capacity. X3 is an innovative tablet press machine in small-scale and medium-scale production, and employs many of KORSCH's latest technologies.

SFP specializes in single-layer tablet production, and MFP can produce single-layer and Bi-layer tablets. Both share the same mechanical platform for unprecedented efficiency.
It also fits into the concept of smart factories (Pharma 4.0), allowing process control and parameter management to be integrated with external systems. PharmaView® (as option) enables intuitive operations such as guided hands-free setup, operation and maintenance within virtual reality.

"XL400" Multi function rotary tablet press machine

XL400 is the most versatile tablet press machine in KORSCH lineup.
By using modular parts, it is possible to change the formats in 8 ways, including single-layer, Bi-layer and Tri-layer tablet (also core-coating and Chip in tablet). XL400 has SFP type which specializes in single-layer tablet production and MFP type which is multifunctional tablet press machine that can also produce multi-layer tablet, they both share a common platform.

Each part and cam-mounted truck are modularized and designed based on "Plug and Play" concept, and can be easily attached / detached without tools. KORSCH's unique designs such as patented compression columns, carrier plates and air cushion dampers etc. are incorporated to achieve extremely low vibration and noise levels (less than 80dB) even though XL400 is for large-scale production. In addition, by storing the main components in the back cabinet, the compression zone is much wider to improve the cleanliness and workability during maintenance.

Also, by connecting with PharmaCheck, it is possible to measure the tablet weight, hardness and thickness according to the sampling time interval. If there is a deviation between the measured value and the target value, then it applies a feedback loop to XL400 and automatically correct the parameters. It also complies with "21 CFR Part 11" The audit trail is available to be stored as the batch data which is including event logs and alarm history etc.

"XT600" High speed double side rotary tablet press machine

XL600 is a high-speed double-sided rotary tablet press machine specialized in the pharmaceutical and food fields.
KORSCH's technology possessed by other mass-production machine is of course included, XT600 is pursuing higher speed, more production, workability, and cleanability.

Designed for 24-hour production, this tablet press machine boasts a production capacity of up to 1 million tablets per hour. Bi-layer tablet production is also possible by installing a modular cam track and a conversion kit (optional) for Bi-layer. In the case of Bi-layer tablet production, each pressure is individually sampled and monitored during compression of the first and second layers, and if the pressure range exceeds the preset value, this tablet is individually rejected.

Even though the corner columns are placed at the four corners of the machine, the guard doors are large on four sides, and dust collection hoses, wiring, and peripherals are stored in these corner columns to improve operator operability, visibility, and cleanability. The noise and vibration levels are kept very low, which greatly improves the working environment of the operator.

The on-board 19-inch touch screen is extremely intuitive to operate. From this touch screen, the operator can also refer to the format change and maintenance procedures, parts list, etc. through multimedia such as photos and videos.
This machine is fully compliant with 21CFR part 11 and GAMP5, and also supports the creation and storage of the batch report as an audit trail.

WIPCON® - Containment (OEB3 / OEB4,5)

All KORSCH tablet machines are available in containment option (OEB3) and WIPCON® (OEB4,5), depending on the toxicity and risk of the highly active substance.
Containment option includes a negative pressure control (air handling), air supply HEPA filter, glove ports and RTPs. WIPCON® are equipped with a washing nozzle for WIP (Wash-in-Place) and air drying system, enabling automatic cleaning with the stored recipe (cleaning step / temperature / flow rate etc.) in PLC
In addition, the peripheral devices such as isolator, deduster, metal checker and IPC (In-Process Control) system can also be integrated under the WIPCON® system, making it possible to build a fully integrated containment system.

KORSCH can offer these tableting line solutions in a variety of layout arrangements.

Tabletting Products

- Single-layer
- Bi-layer
- Tri-layer
- Core coating
- Chip in tablet
- Special shape tablet

Supported applications

- Tablets
- Ramune candy
- Candy
- Chewing gum
- Batteries
- Cleaning agents
- Catalysts
- Magnets
- Sintered alloys
- Airbag tablets